Concepedia

Crispr-based Genome Engineering

CRISPR-Based Genome Engineering is a molecular technique that enables precise, targeted modification of genomic sequences in living organisms through the programmable DNA-binding and cleavage activity of CRISPR-Cas systems.

2.5K

Publications

319.4K

Citations

14.3K

Authors

2.5K

Institutions

Publications per year

2017–2026

1.9K

Variants

Crispr Genome Engineering

Parents

Publications

2.5K

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations

, , +16

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

, , +14

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text

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Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G. Doench, Nicolò Fusi, Meagan E. Sullender et al. · Nature Biotechnology · 2016 · 5K citations

, , +13

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

Haoyi Wang, Hui Yang, Chikdu Shivalila et al. · Cell · 2013 · 3.6K citations · Full text

, , +14

1–5 of 2.5K

Authors

14.3K

  1. JA
    Jennifer A. Doudna

    University of California, Berkeley, United States

    23 publications · 6.8K citations

    22

    h-index

  2. GM
    George M. Church

    Harvard University, United States

    23 publications · 15.6K citations

    21

    h-index

  3. FZ
    Feng Zhang

    Broad Institute, United States

    21 publications · 41.5K citations

    20

    h-index

  4. LS
    Lei S. Qi

    Stanford University, United States

    16 publications · 7.1K citations

    15

    h-index

  5. JK
    Jin‐Soo Kim

    Seoul National University, South Korea

    17 publications · 8.3K citations

    13

    h-index

1–5 of 14.3K

Institutions

2.5K

  1. Chinese Academy of Sciences

    Beijing, China

    69 h-index

    754 publications

    120.5K citations

  2. Harvard University

    Cambridge, United States

    58 h-index

    463 publications

    295.2K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    53 h-index

    167 publications

    48.2K citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    50 h-index

    238 publications

    239.2K citations

  5. University of Chinese Academy of Sciences

    Beijing, China

    46 h-index

    303 publications

    35.8K citations

  6. University of California, Berkeley

    Berkeley, United States

    46 h-index

    256 publications

    52.9K citations

  7. Broad Institute

    Cambridge, United States

    44 h-index

    217 publications

    242.2K citations

  8. University of California, San Francisco

    San Francisco, United States

    31 h-index

    238 publications

    71.6K citations

1–8 of 2.5K

Venues

  1. Scientific Reports

    101 publications · 12.1K citations

    57

    h-index

  2. Nature Communications

    71 publications · 9.4K citations

    44

    h-index

  3. Nature Biotechnology

    48 publications · 37.1K citations

    42

    h-index

  4. ACS Synthetic Biology

    59 publications · 3.9K citations

    36

    h-index

  5. Nature

    41 publications · 16K citations

    31

    h-index

1–5