Nicolò Fusi

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G. Doench, Nicolò Fusi, Meagan E. Sullender et al. · Nature Biotechnology · 2016 · 4.7K citations · Full text

Systems Biology, Off-target Effect, Natural Sciences +10

Gaussian Processes for Big Data

James Hensman, Nicolò Fusi, Neil D. Lawrence · arXiv (Cornell University) · 2013 · 452 citations · Full text

Latent Modeling, Engineering, Machine Learning +11

Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs

Jennifer Listgarten, Michael M. Weinstein, Benjamin P. Kleinstiver et al. · Nature Biomedical Engineering · 2018 · 320 citations · Full text

Off-target Activities, Engineering, Genome Surgery +13

Orthologous CRISPR–Cas9 enzymes for combinatorial genetic screens

Fadi J. Najm, Christine Strand, Katherine Donovan et al. · Nature Biotechnology · 2017 · 289 citations · Full text

Genetics, Genetic Engineering, Molecular Biology +6

A foundation model for clinical-grade computational pathology and rare cancers detection

Eugene Vorontsov, Alican Bozkurt, Adam Casson et al. · Nature Medicine · 2024 · 287 citations · Full text