Jennifer Listgarten

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G. Doench, Nicolò Fusi, Meagan E. Sullender et al. · Nature Biotechnology · 2016 · 4.7K citations · Full text

Systems Biology, Off-target Effect, Natural Sciences +10

FaST linear mixed models for genome-wide association studies

Christoph Lippert, Jennifer Listgarten, Ying Liu et al. · Nature Methods · 2011 · 1.3K citations

Genome-wide Association Study, Genotype-phenotype Association, Statistical Genetics +6

Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs

Jennifer Listgarten, Michael M. Weinstein, Benjamin P. Kleinstiver et al. · Nature Biomedical Engineering · 2018 · 320 citations · Full text

Off-target Activities, Engineering, Genome Surgery +13

Orthologous CRISPR–Cas9 enzymes for combinatorial genetic screens

Fadi J. Najm, Christine Strand, Katherine Donovan et al. · Nature Biotechnology · 2017 · 289 citations · Full text

Genetics, Genetic Engineering, Molecular Biology +6

Epigenome-wide association studies without the need for cell-type composition

James Zou, Christoph Lippert, David Heckerman et al. · Nature Methods · 2014 · 233 citations

Genome-wide Association Study, Epigenome-wide Association Studies, Epigenomics +5