FaST linear mixed models for genome-wide association studies

Christoph Lippert, Jennifer Listgarten, Ying Liu, +3

Nature Methods

Genome-wide Association StudyGenotype-phenotype AssociationStatistical GeneticsBiostatisticsPublic Health +4

Whole-genome sequencing of multiple Arabidopsis thaliana populations

Jun Cao, Korbinian Schneeberger, Stephan Ossowski, +14

Nature Genetics

BiologyWhole-genome SequencingGeneticsGenetic VariationGenome Sequencing +4

Epigenome-wide association studies without the need for cell-type composition

James Zou, Christoph Lippert, David Heckerman, +2

Nature Methods

Genome-wide Association StudyEpigenome-wide Association StudiesEpigenomicsOmicsSystems Biology +3

Time to reality check the promises of machine learning-powered precision medicine

Jack Wilkinson, Kellyn F Arnold, Eleanor J. Murray, +9

The Lancet Digital Health

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies

Daniel Reichart, Eric L. Lindberg, Henrike Maatz, +51

Science

Cardiac MuscleHeart FailureGeneticsCardiac Progenitor CellsCongenital Heart Anomaly +14

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control

István Bartha, Jonathan M. Carlson, Chanson J. Brumme, +25

eLife

Genome-wide Association StudyViral EvolutionSelection PressuresMedicineGenetics +13

Profiling of Short-Tandem-Repeat Disease Alleles in 12,632 Human Whole Genomes

Haibao Tang, Ewen F. Kirkness, Christoph Lippert, +13

The American Journal of Human Genetics

GeneticsGenetic EpidemiologyMolecular GeneticsDisease Gene IdentificationGenomics +19

Identification of individuals by trait prediction using whole-genome sequencing data

Christoph Lippert, Riccardo Sabatini, M. Cyrus Maher, +25

Proceedings of the National Academy of Sciences

Efficient set tests for the genetic analysis of correlated traits

Francesco Paolo Casale, Barbara Rakitsch, Christoph Lippert, +1

Nature Methods

Genome-wide Association StudyGenetic AnalysisLinkage DisequilibriumGenotype-phenotype AssociationMedicine +8

A Lasso multi-marker mixed model for association mapping with population structure correction

Barbara Rakitsch, Christoph Lippert, Oliver Stegle, +1

Bioinformatics