One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
Cell · 2013 · 3.5K citations · 23 references
Off-target EffectEngineeringGenome SurgeryGeneticsCrispr/cas-mediated Genome EngineeringOne-step GenerationSynthetic BiologyGenetic EngineeringGenome EngineeringGene EditingGenome EditingSystems BiologyMedicineMice Carrying MutationsCrispr
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