Bioactive Crude Extracts from Four Bacterial Isolates of Marine Sediments from Red Sea , Gulf of Aqaba , Jordan

Abstract

Escalation in number of resistant pathogens and diseases enhanced scientists to explore the unconventional habitats for bioactive compounds. Marine microorganisms represent a promising source for natural products due to the incredible diversity of chemical compounds that were isolated. Due to distinctive features and biodiversity of Red Sea biota, it was selected as a resource for isolation of bacteria with interesting bioactivity. Detection of bioactivity was performed using antimicrobial and antioxidant assays. Four bacterial isolates were found to have bioactivity at least in one assay. Crude extract of Brevibacterium sp. has weak antibacterial and moderate antioxidant effects, Moraxella sp. with weak antibacterial crude extract, and Corynebacterium sp. with potent antioxidant activity. Therefore, sediment marine bacteria represent an interesting source for antimicrobial and antioxidant secondary metabolites.