Concepedia

Ubiquitin binding mediates the NF-κB inhibitory potential of ABIN proteins

Sebastian Wagner, Isabelle Carpentier, Vladimir V. Rogov, Marja Kreike, Fumiyo Ikeda, Frank Löhr, C-J Wu, Jonathan D. Ashwell, Volker Dötsch, Rudi Beyaert

Oncogene · 2008 · 222 citations · 18 references

DOI

Concepts

References

18

Activation of IKK by TNFα Requires Site-Specific Ubiquitination of RIP1 and Polyubiquitin Binding by NEMO

Chee-Kwee Ea, Li Deng, Zong-Ping Xia et al. · Molecular Cell · 2006 · 981 citations · Full text

, , +14

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation

Chuan-Jin Wu, Dietrich B. Conze, Tao Li et al. · Nature Cell Biology · 2006 · 599 citations

, , +10

Bcl10 activates the NF-κB pathway through ubiquitination of NEMO

Honglin Zhou, Ingrid E. Wertz, Karen O’Rourke et al. · Nature · 2003 · 526 citations

, , +7

The Zinc Finger Protein A20 Inhibits TNF-induced NF-κB–dependent Gene Expression by Interfering with an RIP- or TRAF2-mediated Transactivation Signal and Directly Binds to a Novel NF-κB–inhibiting Protein ABIN

Karen Heyninck, Dirk De Valck, Wim Vanden Berghe et al. · The Journal of Cell Biology · 1999 · 297 citations · Full text

, , +17

Optineurin Negatively Regulates TNFα- Induced NF-κB Activation by Competing with NEMO for Ubiquitinated RIP

Guozhi Zhu, Chuan-Jin Wu, Yongge Zhao et al. · Current Biology · 2007 · 283 citations · Full text

, , +12