Chuan-Jin Wu

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation

Chuan-Jin Wu, Dietrich B. Conze, Tao Li et al. · Nature Cell Biology · 2006 · 596 citations

Transcriptional Regulation, Signal Transduction, Signaling Pathway +14

Optineurin Negatively Regulates TNFα- Induced NF-κB Activation by Competing with NEMO for Ubiquitinated RIP

Guozhi Zhu, Chuan-Jin Wu, Yongge Zhao et al. · Current Biology · 2007 · 277 citations · Full text

Inflammation, Signal Transduction, Disease Pathophysiology +7

Structural Basis for Recognition of Diubiquitins by NEMO

Yu-Chih Lo, Su‐Chang Lin, Carla C. Rospigliosi et al. · Molecular Cell · 2009 · 255 citations · Full text

Molecular Characterization, Bioanalysis, Molecular Biology +4

Lys63-Linked Polyubiquitination of IRAK-1 Is Required for Interleukin-1 Receptor- and Toll-Like Receptor-Mediated NF-κB Activation

Dietrich B. Conze, Chuan-Jin Wu, James A. Thomas et al. · Molecular and Cellular Biology · 2008 · 227 citations · Full text

Irak-1 Is Required, Innate Immune System, Immune Regulation +24

Rationally designed anti-HER2/neu peptide mimetic disables P185HER2/neu tyrosine kinases in vitro and in vivo

Byeong‐Woo Park, Hongtao Zhang, Chuan-Jin Wu et al. · Nature Biotechnology · 2000 · 198 citations · Full text