Concepedia

Rationally designed anti-HER2/neu peptide mimetic disables P185HER2/neu tyrosine kinases in vitro and in vivo

Byeong‐Woo Park, Hongtao Zhang, Chuan-Jin Wu, Alan Berezov, Xin Zhang, Raj Dua, Qiang Wang, Gary D. Kao, Donald M. O’Rourke, Mark I. Greene,

Nature Biotechnology · 2000 · 199 citations · 33 references

DOIFull text

Open access

Concepts

References

33

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

, , +14

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

Morten Hansen, Svend Erik Nielsen, Kurt Berg · Journal of Immunological Methods · 1989 · 3.5K citations

, , +11

Humanization of an anti-p185HER2 antibody for human cancer therapy.

Paul Carter, Leonard G. Presta, C Gorman et al. · Proceedings of the National Academy of Sciences · 1992 · 1.9K citations

, , +16

Canonical structures for the hypervariable regions of immunoglobulins

Cyrus Chothia, Arthur M. Lesk · Journal of Molecular Biology · 1987 · 1.4K citations

, , +14

Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts.

José Baselga, Larry Norton, Joan Albanell et al. · PubMed · 1998 · 1K citations

, , +15