Jonathan D. Ashwell

Ubiquitin Protein Ligase Activity of IAPs and Their Degradation in Proteasomes in Response to Apoptotic Stimuli

Yili Yang, Shengyun Fang, Jane P. Jensen et al. · Science · 2000 · 977 citations

Mitophagy, Proteasome Inhibitors, Apoptosis +24

Outer Membrane Vesicles of a Human Commensal Mediate Immune Regulation and Disease Protection

Yue Shen, Maria Letizia Giardino Torchia, Gregory Lawson et al. · Cell Host & Microbe · 2012 · 683 citations · Full text

Extracellular Vesicles, Outer Membrane Vesicles, Immune Regulation +7

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation

Chuan-Jin Wu, Dietrich B. Conze, Tao Li et al. · Nature Cell Biology · 2006 · 596 citations

Transcriptional Regulation, Signal Transduction, Signaling Pathway +14

Genomic instability in Gadd45a-deficient mice

M. Christine Hollander, M. Saeed Sheikh, Dmitry V. Bulavin et al. · Nature Genetics · 1999 · 516 citations

Knockout Mouse, Genome Instability, Genetics +4

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

Xiaoming Li, Yili Yang, Jonathan D. Ashwell · Nature · 2002 · 446 citations

Protein Function, Signal Transduction, Signaling Pathway +8