Dirk De Valck

The Zinc Finger Protein A20 Inhibits TNF-induced NF-κB–dependent Gene Expression by Interfering with an RIP- or TRAF2-mediated Transactivation Signal and Directly Binds to a Novel NF-κB–inhibiting Protein ABIN

Karen Heyninck, Dirk De Valck, Wim Vanden Berghe et al. · The Journal of Cell Biology · 1999 · 297 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases

Dirk De Valck, Dong‐Yan Jin, Karen Heyninck et al. · Oncogene · 1999 · 139 citations

Life Sciences, Cell Biology, Molecular Biology +15

Effect of bcl-2 proto-oncogene expression on cellular sensitivity to tumor necrosis factor-mediated cytotoxicity.

Bart Vanhaesebroeck, John C. Reed, Dirk De Valck et al. · PubMed · 1993 · 106 citations

Medicine, Cell Biology, Oncology +14

TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.

Walter Fiers, Rudi Beyaert, Elke Boone et al. · PubMed · 1997 · 102 citations

Life Sciences, Cell Biology, Immunology +14

Identification of a Novel A20-binding Inhibitor of Nuclear Factor-κB Activation Termed ABIN-2

Sofie Van Huffel, Filip Delaei, Karen Heyninck et al. · Journal of Biological Chemistry · 2001 · 95 citations · Full text

Life Sciences, Immunology, Molecular Biology +17