Bart Vanhaesebroeck

The PI3K–PDK1 connection: more than just a road to PKB

Bart Vanhaesebroeck, Dario R. Alessi · Biochemical Journal · 2000 · 1.6K citations · Full text

Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.

Klaus Schulze‐Osthoff, Annette Bakker, Bart Vanhaesebroeck et al. · Journal of Biological Chemistry · 1992 · 940 citations · Full text

Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice

Klaus Okkenhaug, Antonio Bilancio, Géraldine Farjot et al. · Science · 2002 · 929 citations

Immunology, Cell Death, Immunologic Mechanism +17

Wortmannin Inactivates Phosphoinositide 3-Kinase by Covalent Modification of Lys-802, a Residue Involved in the Phosphate Transfer Reaction

Matthias P. Wymann, Ginette Bulgarelli-Leva, Marketa Zvelebil et al. · Molecular and Cellular Biology · 1996 · 677 citations · Full text

Signal Transduction, Biochemistry, Natural Sciences +13

Cloning and Characterization of a G Protein-Activated Human Phosphoinositide-3 Kinase

Borislav Stoyanov, Stefano Volinia, Theodor Hanck et al. · Science · 1995 · 675 citations