Concepedia

The mTOR Inhibitor RAD001 Sensitizes Tumor Cells to DNA-Damaged Induced Apoptosis through Inhibition of p21 Translation

Iwan Beuvink, Anne Boulay, Stefano Fumagalli, Frédéric Zilbermann, Stephan Ruetz, Terence O’Reilly, François Natt, Jonathan Hall, Heidi A. Lane, George Thomas

Cell · 2005 · 490 citations · 36 references

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36

WAF1, a potential mediator of p53 tumor suppression

Wafik S. El‐Deiry, Takashi Tokino, Victor E. Velculescu et al. · Cell · 1993 · 8.4K citations

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New functional activities for the p21 family of CDK inhibitors.

Joshua LaBaer, Michelle D. Garrett, Lauren Stevenson et al. · Genes & Development · 1997 · 1.4K citations · Full text

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Translational control of gene expression

Ernest M. Hannig · BioEssays · 2001 · 1.2K citations

, , +17

The p21Cip1 and p27Kip1 CDK ‘inhibitors’ are essential activators of cyclin D‐dependent kinases in murine fibroblasts

Mangeng Cheng, Paul Olivier, J. Alan Diehl et al. · The EMBO Journal · 1999 · 1.1K citations · Full text

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Insulin Activation of Rheb, a Mediator of mTOR/S6K/4E-BP Signaling, Is Inhibited by TSC1 and 2

Attila Garami, Fried Zwartkruis, Takahiro Nobukuni et al. · Molecular Cell · 2003 · 1K citations · Full text

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