Stefano Fumagalli

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

Sung Hee Um, Francesca Frigerio, Mitsuhiro Watanabe et al. · Nature · 2004 · 1.7K citations · Full text

Medicine, Biochemistry, Endocrinology +14

Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k

Harold B.J. Jefferies, Stefano Fumagalli, Patrick B. Dennis et al. · The EMBO Journal · 1997 · 932 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

<i>S6K1</i> ^−/− / <i>S6K2</i> ^−/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway

Mario Pende, Sung Hee Um, Virginie Mieulet et al. · Molecular and Cellular Biology · 2004 · 733 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Disruption of the p70s6k/p85s6k gene reveals a small mouse phenotype and a new functional S6 kinase

Hiroshi Shima, Mario Pende, Yi Chen et al. · The EMBO Journal · 1998 · 633 citations

Life Sciences, Genetics, Molecular Biology +4

The mTOR Inhibitor RAD001 Sensitizes Tumor Cells to DNA-Damaged Induced Apoptosis through Inhibition of p21 Translation

Iwan Beuvink, Anne Boulay, Stefano Fumagalli et al. · Cell · 2005 · 490 citations · Full text

Life Sciences, Oncology, Pharmacology +14