Harold B.J. Jefferies

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k

Harold B.J. Jefferies · The EMBO Journal · 1997 · 929 citations · Full text

Protein Biosynthesis, Mrna Translation, Gene Expression +3

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family.

Harold B.J. Jefferies, Christoph Reinhard, Sara C. Kozma et al. · Proceedings of the National Academy of Sciences · 1994 · 628 citations · Full text

Rapamycin Treatment, Molecular Regulation, Kinase Inactivation +17

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves

Jose A. Gomez‐Sanchez, Lucy Carty, Marta Iruarrizaga‐Lejarreta et al. · The Journal of Cell Biology · 2015 · 454 citations · Full text

A selective PIKfyve inhibitor blocks PtdIns(3,5)P ₂ production and disrupts endomembrane transport and retroviral budding

Harold B.J. Jefferies, Frank T. Cooke, Parmjit Jat et al. · EMBO Reports · 2008 · 297 citations · Full text

Analysis of the transcriptional program induced by Raf in epithelial cells

Almut Schulze, Kerstin Lehmann, Harold B.J. Jefferies et al. · Genes & Development · 2001 · 256 citations · Full text

Transcriptional Regulation, Signaling Pathway, Cell Regulation +17