Frank T. Cooke

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits

Len Stephens, Alan V. Smrcka, Frank T. Cooke et al. · Cell · 1994 · 597 citations

Signal Transduction, Molecular Physiology, Cell Regulation +12

The Gβγ Sensitivity of a PI3K Is Dependent upon a Tightly Associated Adaptor, p101

Len Stephens, A. Eguinoa, Hediye Erdjument‐Bromage et al. · Cell · 1997 · 560 citations · Full text

PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase

Phillip T. Hawkins, A. Eguinoa, Rongguo Qiu et al. · Current Biology · 1995 · 541 citations · Full text

Signal Transduction, Molecular Physiology, Signaling Pathway +9

Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis

Stephen K. Dove, Frank T. Cooke, Michael R. Douglas et al. · Nature · 1997 · 465 citations

Signal Transduction, Osmotic Stress, Biochemistry +7

Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

Stefan Wennström, Phillip T. Hawkins, Frank T. Cooke et al. · Current Biology · 1994 · 437 citations

Molecular Physiology, Signal Transduction, Pdgf-stimulated Membrane +11