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PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase

Phillip T. Hawkins, A. Eguinoa, Rongguo Qiu, David Stokoe, Frank T. Cooke, Rhodri Walters, Stefan Wennström, Lena Claesson‐Welsh, Tony Evans, Marc Symons,

Current Biology · 1995 · 541 citations · 55 references

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55

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

Anne J. Ridley, Hugh F. Paterson, Caroline L. Johnston et al. · Cell · 1992 · 3.7K citations

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A brain serine/threonine protein kinase activated by Cdc42 and Rac1

Edward Manser, Thomas Leung, Harfizah Salihuddin et al. · Nature · 1994 · 1.5K citations

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Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses

Alexandre Arcaro, Matthias P. Wymann · Biochemical Journal · 1993 · 1.1K citations · Full text

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Phosphatidylinositol 3′‐kinase is activated by association with IRS‐1 during insulin stimulation.

Jonathan Backer, Martin G. Myers, Steven E. Shoelson et al. · The EMBO Journal · 1992 · 1K citations · Full text

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Phosphatidylinositol 3-Kinase Activation Is Required for Insulin Stimulation of pp70 S6 Kinase, DNA Synthesis, and Glucose Transporter Translocation

Bentley Cheatham, Chris J. Vlahos, Lynn Cheatham et al. · Molecular and Cellular Biology · 1994 · 1K citations · Full text

, , +17