David Stokoe

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Georgia Hatzivassiliou, Kyung Song, Ivana Yen et al. · Nature · 2010 · 1.6K citations · Full text

Signaling Pathway, Receptor Tyrosine Kinase, Mapk Pathway +8

Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors

Ingo K. Mellinghoff, Maria Y. Wang, Igor Vivanco et al. · New England Journal of Medicine · 2005 · 1.4K citations · Full text

Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

Andrew T. Parsa, James S. Waldron, Amith Panner et al. · Nature Medicine · 2006 · 1.3K citations

Tumor Biology, Cell Regulation, Glioma +8

Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

David Stokoe, Terry Copeland, Piers R. J. Gaffney et al. · Science · 1997 · 1.2K citations

A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling

Zachary A. Knight, Beatriz González, Morri E. Feldman et al. · Cell · 2006 · 1.1K citations · Full text

Molecular Pharmacology, Metabolic Syndrome, Signal Transduction +14