Piers R. J. Gaffney

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα

Dario R. Alessi, Stephen R. James, C. Peter Downes et al. · Current Biology · 1997 · 2.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

David Stokoe, Terry Copeland, Piers R. J. Gaffney et al. · Science · 1997 · 1.2K citations

Life Sciences, Cancer Biology, Cell Biology +15

Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B

Len Stephens, Karen E. Anderson, David Stokoe et al. · Science · 1998 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +17

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

Dario R. Alessi, Mária Deák, Antonio Casamayor et al. · Current Biology · 1997 · 743 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2

Anudharan Balendran, Antonio Casamayor, Mária Deák et al. · Current Biology · 1999 · 441 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +5