Len Stephens

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

Edward H. Walker, Michael E. Pacold, Olga Perišić et al. · Molecular Cell · 2000 · 1.2K citations · Full text

Molecular Pharmacology, Signal Transduction, Biochemistry +11

Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B

Len Stephens, Karen E. Anderson, David Stokoe et al. · Science · 1998 · 1.1K citations

Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase γ

Michael E. Pacold, Sabine Suire, Olga Perišić et al. · Cell · 2000 · 624 citations · Full text

Crystal Structure, Signal Transduction, Molecular Physiology +12

Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage

Ivan L. Ângulo, Oscar Vadas, Fabien Garçon et al. · Science · 2013 · 609 citations · Full text

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits

Len Stephens, Alan V. Smrcka, Frank T. Cooke et al. · Cell · 1994 · 597 citations

Signal Transduction, Molecular Physiology, Cell Regulation +12