Oscar Vadas

Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage

Ivan L. Ângulo, Oscar Vadas, Fabien Garçon et al. · Science · 2013 · 623 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α ( <i>PIK3CA</i> )

John E. Burke, Olga Perišić, Glenn R. Masson et al. · Proceedings of the National Academy of Sciences · 2012 · 320 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism

Xuxiao Zhang, Oscar Vadas, Olga Perišić et al. · Molecular Cell · 2011 · 208 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

G Protein–Coupled Receptor–Mediated Activation of p110β by Gβγ Is Required for Cellular Transformation and Invasiveness

Hashem A. Dbouk, Oscar Vadas, Aliaksei Shymanets et al. · Science Signaling · 2012 · 149 citations

Life Sciences, Biochemistry, Cell Biology +17

Molecular determinants of PI3Kγ-mediated activation downstream of G-protein–coupled receptors (GPCRs)

Oscar Vadas, Hashem A. Dbouk, Aliaksei Shymanets et al. · Proceedings of the National Academy of Sciences · 2013 · 139 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17