Oscar Vadas

Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage

Ivan L. Ângulo, Oscar Vadas, Fabien Garçon et al. · Science · 2013 · 609 citations · Full text

Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α ( <i>PIK3CA</i> )

John E. Burke, Olga Perišić, Glenn R. Masson et al. · Proceedings of the National Academy of Sciences · 2012 · 311 citations · Full text

Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism

Xuxiao Zhang, Oscar Vadas, Olga Perišić et al. · Molecular Cell · 2011 · 200 citations · Full text

G Protein–Coupled Receptor–Mediated Activation of p110β by Gβγ Is Required for Cellular Transformation and Invasiveness

Hashem A. Dbouk, Oscar Vadas, Aliaksei Shymanets et al. · Science Signaling · 2012 · 146 citations · Full text

Molecular Biology, Cellular Physiology, Tumor Biology +23

Molecular determinants of PI3Kγ-mediated activation downstream of G-protein–coupled receptors (GPCRs)

Oscar Vadas, Hashem A. Dbouk, Aliaksei Shymanets et al. · Proceedings of the National Academy of Sciences · 2013 · 136 citations · Full text

P101 Subunits, Molecular Pharmacology, Signaling Pathway +20