Xuxiao Zhang

Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism

Xuxiao Zhang, Oscar Vadas, Olga Perišić et al. · Molecular Cell · 2011 · 208 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology

Florent Beaufils, Nataša Cmiljanović, Vladimir Cmiljanović et al. · Journal of Medicinal Chemistry · 2017 · 134 citations · Full text

Medicine, Oncology, Pharmacology +14

Prevailing PA Mutation K356R in Avian Influenza H9N2 Virus Increases Mammalian Replication and Pathogenicity

Guanlong Xu, Xuxiao Zhang, Weihua Gao et al. · Journal of Virology · 2016 · 106 citations · Full text

Life Sciences, Biology, Infectious Diseases +17

Highly Pathogenic Avian Influenza H5N6 Viruses Exhibit Enhanced Affinity for Human Type Sialic Acid Receptor and In-Contact Transmission in Model Ferrets

Honglei Sun, Juan Pu, Yandi Wei et al. · Journal of Virology · 2016 · 82 citations · Full text

Life Sciences, Infectious Diseases, Host-pathogen Interactions +16

PKCβ Phosphorylates PI3Kγ to Activate It and Release It from GPCR Control

Romy Walser, John E. Burke, Elena Gogvadze et al. · PLoS Biology · 2013 · 79 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17