Hashem A. Dbouk

Somatic Mutations in p85α Promote Tumorigenesis through Class IA PI3K Activation

Bijay S. Jaiswal, Vasantharajan Janakiraman, Noelyn M. Kljavin et al. · Cancer Cell · 2009 · 286 citations · Full text

Somatic Variant, Somatic Mutations, Cell Regulation +8

Connexins: a myriad of functions extending beyond assembly of gap junction channels

Hashem A. Dbouk, Rana Mroue, Marwan El‐Sabban et al. · Cell Communication and Signaling · 2009 · 259 citations · Full text

G Protein–Coupled Receptor–Mediated Activation of p110β by Gβγ Is Required for Cellular Transformation and Invasiveness

Hashem A. Dbouk, Oscar Vadas, Aliaksei Shymanets et al. · Science Signaling · 2012 · 146 citations · Full text

Molecular Biology, Cellular Physiology, Tumor Biology +23

Class IA PI3K p110β Subunit Promotes Autophagy through Rab5 Small GTPase in Response to Growth Factor Limitation

Zhixun Dou, Ji-An Pan, Hashem A. Dbouk et al. · Molecular Cell · 2013 · 136 citations · Full text

Cell Autophagy, Mitophagy, Signal Transduction +10

Molecular determinants of PI3Kγ-mediated activation downstream of G-protein–coupled receptors (GPCRs)

Oscar Vadas, Hashem A. Dbouk, Aliaksei Shymanets et al. · Proceedings of the National Academy of Sciences · 2013 · 136 citations · Full text

P101 Subunits, Molecular Pharmacology, Signaling Pathway +20