Edward H. Walker

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

Edward H. Walker, Michael E. Pacold, Olga Perišić et al. · Molecular Cell · 2000 · 1.2K citations · Full text

Molecular Pharmacology, Signal Transduction, Biochemistry +11

Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase γ

Michael E. Pacold, Sabine Suire, Olga Perišić et al. · Cell · 2000 · 624 citations · Full text

Crystal Structure, Signal Transduction, Molecular Physiology +12

Structural insights into phosphoinositide 3-kinase catalysis and signalling

Edward H. Walker, Olga Perišić, Christian Ried et al. · Nature · 1999 · 490 citations

Signal Transduction, Signaling Pathway, Biochemistry +6

The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins

Rachael P. Huntley, Sandra Healy, Donna Freeman et al. · Plant Molecular Biology · 1998 · 160 citations

Bicyclic Peptides with Optimized Ring Size Inhibit Human Plasma Kallikrein and its Orthologues While Sparing Paralogous Proteases

Vanessa Baeriswyl, Helen Rapley, Lisa Pollaro et al. · ChemMedChem · 2012 · 70 citations · Full text

Macrocyclic Rings, Peptide Engineering, Immunology +18