Sung Hee Um

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

Sung Hee Um, Francesca Frigerio, Mitsuhiro Watanabe et al. · Nature · 2004 · 1.6K citations · Full text

Obesity, Metabolic Syndrome, Nutrition +11

<i>S6K1</i> ^−/− / <i>S6K2</i> ^−/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway

Mario Pende, Sung Hee Um, Virginie Mieulet et al. · Molecular and Cellular Biology · 2004 · 731 citations · Full text

Disruption of the Mouse mTOR Gene Leads to Early Postimplantation Lethality and Prohibits Embryonic Stem Cell Development

Yann‐Gaël Gangloff, Matthias Mueller, Stephen G. Dann et al. · Molecular and Cellular Biology · 2004 · 477 citations · Full text

Genetics, Cell Proliferation, Mtor Protein Levels +21

Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance

Frédéric Tremblay, Sophie Brûlé, Sung Hee Um et al. · Proceedings of the National Academy of Sciences · 2007 · 458 citations · Full text

Amino Acids, Metabolic Disorder, Obesity-induced Insulin Resistance +19

S6K1 Plays a Critical Role in Early Adipocyte Differentiation

Larissa S. Carnevalli, Kouhei Masuda, Francesca Frigerio et al. · Developmental Cell · 2010 · 202 citations · Full text

Molecular Physiology, Developmental Biology, Metabolic Regulation +4