Amino Acid and Insulin Signaling via the mTOR/p70 S6 Kinase Pathway

Frédéric Tremblay, André Marette

Journal of Biological Chemistry

Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance

Frédéric Tremblay, Sophie Brûlé, Sung Hee Um, +8

Proceedings of the National Academy of Sciences

Amino AcidsMetabolic DisorderObesity-induced Insulin ResistanceMetabolic RemodelingIrs-1 Ser-1101 +17

Overactivation of S6 Kinase 1 as a Cause of Human Insulin Resistance During Increased Amino Acid Availability

Frédéric Tremblay, Michael Krebs, Luce Dombrowski, +7

Diabetes

Defective Insulin-Induced GLUT4 Translocation in Skeletal Muscle of High Fat–Fed Rats Is Associated With Alterations in Both Akt/Protein Kinase B and Atypical Protein Kinase C (ζ/λ) Activities

Frédéric Tremblay, Charles Lavigne, Hélène Jacques, +1

Diabetes

Activation of the Mammalian Target of Rapamycin Pathway Acutely Inhibits Insulin Signaling to Akt and Glucose Transport in 3T3-L1 and Human Adipocytes

Frédéric Tremblay, AnneMarie Gagnon, Alain Veilleux, +2

Endocrinology

Rapamycin TreatmentMtor PathwayMetabolic RemodelingHuman AdipocytesInsulin Signaling +15

Prevention of skeletal muscle insulin resistance by dietary cod protein in high fat-fed rats

Charles Lavigne, Frédéric Tremblay, Geneviève Asselin, +2

American Journal of Physiology-Endocrinology and Metabolism

Normal Food Intake and Body Weight in Mice Lacking the G Protein-Coupled Receptor GPR39

Frédéric Tremblay, Mylène Perreault, Lori D. Klaman, +3

Endocrinology

NutritionGpr39 GeneFood IntakeExperimental NutritionGastrointestinal Peptide Hormone +18

Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation

Lucía Barbier‐Torres, Karen A. Fortner, Paula Iruzubieta, +23

Nature Communications

Lipid PeroxidationPathologyFatty Liver DiseaseOxidative StressMetabolic Syndrome +26

Dietary Cod Protein Restores Insulin-Induced Activation of Phosphatidylinositol 3-Kinase/Akt and GLUT4 Translocation to the T-Tubules in Skeletal Muscle of High-Fat-Fed Obese Rats

Frédéric Tremblay, Charles Lavigne, Hélène Jacques, +1

Diabetes

Disruption of G Protein-Coupled Receptor 39 Impairs Insulin Secretion in Vivo

Frédéric Tremblay, Ann-Marie Richard, Sarah Will, +4

Endocrinology