Frédéric Tremblay

Amino Acid and Insulin Signaling via the mTOR/p70 S6 Kinase Pathway

Frédéric Tremblay, André Marette · Journal of Biological Chemistry · 2001 · 529 citations · Full text

Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance

Frédéric Tremblay, Sophie Brûlé, Sung Hee Um et al. · Proceedings of the National Academy of Sciences · 2007 · 458 citations · Full text

Amino Acids, Metabolic Disorder, Obesity-induced Insulin Resistance +19

Overactivation of S6 Kinase 1 as a Cause of Human Insulin Resistance During Increased Amino Acid Availability

Frédéric Tremblay, Michael Krebs, Luce Dombrowski et al. · Diabetes · 2005 · 363 citations

Defective Insulin-Induced GLUT4 Translocation in Skeletal Muscle of High Fat–Fed Rats Is Associated With Alterations in Both Akt/Protein Kinase B and Atypical Protein Kinase C (ζ/λ) Activities

Frédéric Tremblay, Charles Lavigne, Hélène Jacques et al. · Diabetes · 2001 · 209 citations · Full text

Activation of the Mammalian Target of Rapamycin Pathway Acutely Inhibits Insulin Signaling to Akt and Glucose Transport in 3T3-L1 and Human Adipocytes

Frédéric Tremblay, AnneMarie Gagnon, Alain Veilleux et al. · Endocrinology · 2004 · 173 citations · Full text

Rapamycin Treatment, Mtor Pathway, Metabolic Remodeling +17