Fried Zwartkruis

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

Johan de Rooij, Fried Zwartkruis, Mark H. G. Verheijen et al. · Nature · 1998 · 2K citations

Signal Transduction, Molecular Physiology, Biochemistry +7

A genetic screen for mutations affecting embryogenesis in zebrafish

Wolfgang Driever, Lilianna Solnica‐Krezel, Alexander F. Schier et al. · Development · 1996 · 1.3K citations

Insulin Activation of Rheb, a Mediator of mTOR/S6K/4E-BP Signaling, Is Inhibited by TSC1 and 2

Attila Garami, Fried Zwartkruis, Takahiro Nobukuni et al. · Molecular Cell · 2003 · 1K citations · Full text

Molecular Physiology, Signal Transduction, Insulin Activation +10

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase

Takahiro Nobukuni, Manel Joaquin, Marta Roccio et al. · Proceedings of the National Academy of Sciences · 2005 · 747 citations · Full text

Class 3, Amino Acids, Molecular Regulation +20

Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo

Didier Y. R. Stainier, Bernadette Fouquet, Jau‐Nian Chen et al. · Development · 1996 · 625 citations