Manel Joaquin

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

Sung Hee Um, Francesca Frigerio, Mitsuhiro Watanabe et al. · Nature · 2004 · 1.6K citations · Full text

Obesity, Metabolic Syndrome, Nutrition +11

Insulin Activation of Rheb, a Mediator of mTOR/S6K/4E-BP Signaling, Is Inhibited by TSC1 and 2

Attila Garami, Fried Zwartkruis, Takahiro Nobukuni et al. · Molecular Cell · 2003 · 1K citations · Full text

Molecular Physiology, Signal Transduction, Insulin Activation +10

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase

Takahiro Nobukuni, Manel Joaquin, Marta Roccio et al. · Proceedings of the National Academy of Sciences · 2005 · 747 citations · Full text

Class 3, Amino Acids, Molecular Regulation +20

Amino Acids Activate mTOR Complex 1 via Ca2+/CaM Signaling to hVps34

Pawan Gulati, Lawrence D. Gaspers, Stephen G. Dann et al. · Cell Metabolism · 2008 · 362 citations · Full text

Protein Function, Signal Transduction, Molecular Physiology +7

The N-Terminal Phosphorylation of RB by p38 Bypasses Its Inactivation by CDKs and Prevents Proliferation in Cancer Cells

Albert Gubern, Manel Joaquin, Miriam Marqués et al. · Molecular Cell · 2016 · 92 citations · Full text

Signal Transduction, Cell Regulation, Biochemistry +10