Heidi A. Lane

mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt

Kathryn O’Reilly, F. Rojo, Qing‐Bai She et al. · Cancer Research · 2006 · 2.6K citations · Full text

Medicine, Oncology, Pharmacology +16

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

Anne Blangy, Heidi A. Lane, Pierre d'Hérin et al. · Cell · 1995 · 963 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

Pradip K. Majumder, Phillip G. Febbo, Rachel Bikoff et al. · Nature Medicine · 2004 · 956 citations

Medicine, Oncology, Urology +15

Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes.

Heidi A. Lane, Erich A. Nigg · The Journal of Cell Biology · 1996 · 690 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Phase II Randomized Study of Neoadjuvant Everolimus Plus Letrozole Compared With Placebo Plus Letrozole in Patients With Estrogen Receptor–Positive Breast Cancer

José Baselga, Peter van Dam, Alexey Manikhas et al. · Journal of Clinical Oncology · 2009 · 658 citations

Medicine, Oncology, Pharmacology +17