Concepedia

Discovery of sulfonamide–pyrazole γ-secretase inhibitors

Matthew N. Mattson, Martin L. Neitzel, David A. Quincy, Christopher M. Semko, Albert W. Garofalo, Pamela S. Keim, Andrei W. Konradi, Michael A. Pleiss, Hing L. Sham, Elizabeth Brigham,

Bioorganic & Medicinal Chemistry Letters · 2010 · 18 citations · 7 references

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References

7

Flipped Out:  Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors

Alex M. Aronov, Christopher Baker, Guy W. Bemis et al. · Journal of Medicinal Chemistry · 2007 · 122 citations · Full text

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Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension

Gui‐Dong Zhu, Viraj B. Gandhi, Jianchun Gong et al. · Journal of Medicinal Chemistry · 2007 · 62 citations · Full text

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Identification of γ-Secretase Inhibitor Potency Determinants on Presenilin

Byron Zhao, Yu Mei, Martin L. Neitzel et al. · Journal of Biological Chemistry · 2007 · 61 citations · Full text

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Development of CXCR3 antagonists. Part 3: Tropenyl and homotropenyl-piperidine urea derivatives

Robert J. Watson, Daniel R. Allen, Helen L. Birch et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 37 citations · Full text

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Design, synthesis, and structure–activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline γ-secretase inhibitors

Anh P. Truong, Danielle L. Aubele, Gary D. Probst et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 37 citations · Full text

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