Concepedia

Alex M. Aronov

AM

Statistics

Publications

25

Citations

1.6K

H-Index

21

Active since

1998

Affiliations

Vertex Pharmaceuticals (United States)(Current)

University of Washington

Howard Hughes Medical Institute

University of California, San Francisco

University of Maryland, Baltimore

Alex M. Aronov is an author at Vertex Pharmaceuticals (United States) specializing in medicinal chemistry, pharmacology, and drug discovery.

Publications per year

1998–2021

25

Publications

25

Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib)

Ursula A. Germann, Brinley F. Furey, William Markland et al. · Molecular Cancer Therapeutics · 2017 · 234 citations

, , +16

Structure-Guided Design of Potent and Selective Pyrimidylpyrrole Inhibitors of Extracellular Signal-Regulated Kinase (ERK) Using Conformational Control

Alex M. Aronov, Qing Tang, Gabriel Martínez-Botella et al. · Journal of Medicinal Chemistry · 2009 · 145 citations · Full text

, , +17

Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase

Alex M. Aronov, Stephen Suresh, Frederick S. Buckner et al. · Proceedings of the National Academy of Sciences · 1999 · 124 citations · Full text

, , +16

Flipped Out:  Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors

Alex M. Aronov, Christopher Baker, Guy W. Bemis et al. · Journal of Medicinal Chemistry · 2007 · 122 citations · Full text

, , +17

Common Pharmacophores for Uncharged Human Ether-a-go-go-Related Gene (hERG) Blockers

Alex M. Aronov · Journal of Medicinal Chemistry · 2006 · 121 citations

, , +16

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