Concepedia

William Markland

WM

Statistics

Publications

25

Citations

2.6K

H-Index

21

Active since

1986

Affiliations

Vertex Pharmaceuticals (United States)(Current)

MSM Protein Technologies (United States)

Sequenom (United States)

University of Maryland, Baltimore

Horizon Discovery (United Kingdom)

William Markland is an author at Vertex Pharmaceuticals (United States) specializing in life sciences, molecular biology, and virology.

Publications per year

1986–2017

25

Publications

25

Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide

J.L Kim, Kurt Morgenstern, Chao Lin et al. · Cell · 1996 · 728 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Broad-Spectrum Antiviral Activity of the IMP Dehydrogenase Inhibitor VX-497: a Comparison with Ribavirin and Demonstration of Antiviral Additivity with Alpha Interferon

William Markland, Thomas McQuaid, Jugnu Jain et al. · Antimicrobial Agents and Chemotherapy · 2000 · 255 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib)

Ursula A. Germann, Brinley F. Furey, William Markland et al. · Molecular Cancer Therapeutics · 2017 · 234 citations

Medicine, Oncology, Pharmacology +16

Directed evolution of a protein: selection of potent neutrophil elastase inhibitors displayed on M13 fusion phage.

Bruce Roberts, William Markland, Arthur C. Ley et al. · Proceedings of the National Academy of Sciences · 1992 · 198 citations

Life Sciences, Biochemistry, Biotechnology +17

Crystal structure of JNK3: a kinase implicated in neuronal apoptosis

Xiaoling Xie, Yong Gu, Ted Fox et al. · Structure · 1998 · 197 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14

1–5 of 25