Concepedia

Viraj B. Gandhi

VB

Statistics

Publications

10

Citations

733

H-Index

10

Active since

2006

Affiliations

Abbott Fund(Current)

Abbott (United Kingdom)

Viraj B. Gandhi is an author at Abbott Fund specializing in medicinal chemistry, drug discovery, and pharmacology.

Publications per year

2006–2012

10

Publications

10

Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(<i>R</i>)-2-methylpyrrolidin-2-yl]-1<i>H</i>-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

Thomas D. Penning, Gui‐Dong Zhu, Viraj B. Gandhi et al. · Journal of Medicinal Chemistry · 2008 · 269 citations · Full text

, , +14

Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer

Thomas D. Penning, Gui‐Dong Zhu, Viraj B. Gandhi et al. · Bioorganic & Medicinal Chemistry · 2008 · 75 citations · Full text

, , +9

Optimization of Phenyl-Substituted Benzimidazole Carboxamide Poly(ADP-Ribose) Polymerase Inhibitors: Identification of (<i>S</i>)-2-(2-Fluoro-4-(pyrrolidin-2-yl)phenyl)-1<i>H</i>-benzimidazole-4-carboxamide (A-966492), a Highly Potent and Efficacious Inhibitor

Gui‐Dong Zhu, Jianchun Gong, Sheela A. Thomas et al. · Journal of Medicinal Chemistry · 2010 · 71 citations · Full text

, , +15

Design and synthesis of pyridine–pyrazolopyridine-based inhibitors of protein kinase B/Akt

Gui‐Dong Zhu, Jianchun Gong, Viraj B. Gandhi et al. · Bioorganic & Medicinal Chemistry · 2007 · 62 citations · Full text

, , +12

Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension

Gui‐Dong Zhu, Viraj B. Gandhi, Jianchun Gong et al. · Journal of Medicinal Chemistry · 2007 · 62 citations · Full text

, , +16

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