Gary D. Probst

Antibody–Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs

Christopher R. Behrens, Edward Ha, Lawrence Chinn et al. · Molecular Pharmaceutics · 2015 · 150 citations · Full text

Afford Adcs, Immunology, Immunotherapeutics +19

Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer

Shenghong Ma, Tracy Tang, Gary D. Probst et al. · Nature Communications · 2022 · 129 citations · Full text

Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor

Penglie Zhang, Wenrong Huang, Lingyan Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 105 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +10

Ruthenium-Catalyzed Alder Ene Type Reactions. A Formal Synthesis of Alternaric Acid

Barry M. Trost, Gary D. Probst, Andreas Schoop · Journal of the American Chemical Society · 1998 · 96 citations

Medicinal Chemistry, Engineering, Terminal Methylene +15

Treatment of Experimental Autoimmune Encephalomyelitis by Codelivery of Disease Associated Peptide and Dexamethasone in Acetalated Dextran Microparticles

Kevin J. Peine, Mireia Guerau‐de‐Arellano, Priscilla Ming Yi Lee et al. · Molecular Pharmaceutics · 2014 · 71 citations · Full text

Immunodeficiencies, Immunology, Immune Regulation +25