Concepedia

Design, synthesis, and structure–activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline γ-secretase inhibitors

Anh P. Truong, Danielle L. Aubele, Gary D. Probst, Martin L. Neitzel, Chris M. Semko, Simeon Bowers, Darren Dressen, Roy K. Hom, Andrei W. Konradi, Hing L. Sham,

Bioorganic & Medicinal Chemistry Letters · 2009 · 37 citations · 11 references

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11

Global prevalence of dementia: a Delphi consensus study

Cleusa P. Ferri, Martin Prince, Carol Brayne et al. · The Lancet · 2005 · 5.3K citations · Full text

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Readily accessible 12-I-5 oxidant for the conversion of primary and secondary alcohols to aldehydes and ketones

D. B. DESS, J. C. Martin · The Journal of Organic Chemistry · 1983 · 3.1K citations

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Fluorine substituent effects (on bioactivity)

Bruce E. Smart · Journal of Fluorine Chemistry · 2001 · 1.5K citations

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Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain

Harry F. Dovey, Varghese John, J. P. Anderson et al. · Journal of Neurochemistry · 2001 · 879 citations · Full text

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Oral administration of a potent and selective non‐peptidic BACE‐1 inhibitor decreases β‐cleavage of amyloid precursor protein and amyloid‐β production <i>in vivo</i>

Ishrut Hussain, Julie A. Hawkins, David C. Harrison et al. · Journal of Neurochemistry · 2006 · 198 citations · Full text

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