Roy K. Hom

Design, Synthesis, and Crystal Structure of Hydroxyethyl Secondary Amine-Based Peptidomimetic Inhibitors of Human β-Secretase

Michel Maillard, Roy K. Hom, Timothy E. Benson et al. · Journal of Medicinal Chemistry · 2007 · 110 citations · Full text

Design of Substrate-Based Inhibitors of Human β-Secretase

Jay S. Tung, David L. Davis, John P. Anderson et al. · Journal of Medicinal Chemistry · 2001 · 88 citations · Full text

Design and Synthesis of Hydroxyethylene-Based Peptidomimetic Inhibitors of Human β-Secretase

Roy K. Hom, Andrea F. Gailunas, Shumeye Mamo et al. · Journal of Medicinal Chemistry · 2003 · 80 citations · Full text

Medicinal Chemistry, Human β-Secretase, Bioorganic Chemistry +15

Design and Synthesis of Statine-Based Cell-Permeable Peptidomimetic Inhibitors of Human β-Secretase

Roy K. Hom, Larry Y. Fang, Shumeye Mamo et al. · Journal of Medicinal Chemistry · 2003 · 78 citations · Full text

Protein Secretion, Human β-Secretase, Biochemistry +13

Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model

Anh P. Truong, G. Toth, Gary D. Probst et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 48 citations · Full text

Pharmacological Study, Biochemistry, Medicine +9