David L. Davis

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

MP Mattson, Bin Cheng, David L. Davis et al. · Journal of Neuroscience · 1992 · 1.6K citations · Full text

Purification and cloning of amyloid precursor protein β-secretase from human brain

Sukanto Sinha, John P. Anderson, Robin Barbour et al. · Nature · 1999 · 1.6K citations

Neurodegenerative Diseases, Protein Secretion, Molecular Neuroscience +8

Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide

Peter Seubert, Tilman Oltersdorf, M. Lee et al. · Nature · 1993 · 547 citations

Protein Secretion, Protein Assembly, Biochemistry +7

Lack of alzheimer pathology after β-amyloid protein injections in rat brain

Dora Games, Karen Khan, Ferdie Soriano et al. · Neurobiology of Aging · 1992 · 124 citations

Neurodegenerative Diseases, Alzheimer's Disease, Degenerative Pathology +9

Design of Substrate-Based Inhibitors of Human β-Secretase

Jay S. Tung, David L. Davis, John P. Anderson et al. · Journal of Medicinal Chemistry · 2001 · 88 citations · Full text