Hing L. Sham

ABT-378, a Highly Potent Inhibitor of the Human Immunodeficiency Virus Protease

Hing L. Sham, Dale J. Kempf, Akhteruzammen Molla et al. · Antimicrobial Agents and Chemotherapy · 1998 · 468 citations · Full text

Potent, Orally Active Heterocycle-Based Combretastatin A-4 Analogues:  Synthesis, Structure−Activity Relationship, Pharmacokinetics, and In Vivo Antitumor Activity Evaluation

Le Wang, Keith W. Woods, Qun Li et al. · Journal of Medicinal Chemistry · 2002 · 420 citations · Full text

Medicinal Chemistry, Drug Targeting, Oncology +14

Polo-like Kinase 2 (PLK2) Phosphorylates α-Synuclein at Serine 129 in Central Nervous System

Kelly J. Inglis, David Chéreau, Elizabeth Brigham et al. · Journal of Biological Chemistry · 2008 · 266 citations · Full text

Neurodegenerative Diseases, Serine 129, Molecular Neuroscience +12

Discovery of Ritonavir, a Potent Inhibitor of HIV Protease with High Oral Bioavailability and Clinical Efficacy

Dale J. Kempf, Hing L. Sham, Kennan C. Marsh et al. · Journal of Medicinal Chemistry · 1998 · 204 citations · Full text

Immunology, Pharmacotherapy, Antiviral Drug +18

Human Serum Attenuates the Activity of Protease Inhibitors toward Wild-Type and Mutant Human Immunodeficiency Virus

Akhteruzzaman Molla, Sudthida Vasavanonda, Gondi Kumar et al. · Virology · 1998 · 177 citations

Protease Inhibitors, Biochemistry, Medicine +13