Dale J. Kempf

Ordered accumulation of mutations in HIV protease confers resistance to ritonavir

Akhteruzzaman Molla, Marina Korneyeva, Qing Gao et al. · Nature Medicine · 1996 · 768 citations

Life Sciences, Genetics, Molecular Biology +14

Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy

Sarah Palmer, Frank Maldarelli, Ann Wiegand et al. · Proceedings of the National Academy of Sciences · 2008 · 646 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +14

ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.

Dale J. Kempf, Kennan C. Marsh, Jon F. Denissen et al. · Proceedings of the National Academy of Sciences · 1995 · 556 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Design, Activity, and 2.8 Å Crystal Structure of a <i>C</i> ₂ Symmetric Inhibitor Complexed to HIV-1 Protease

John W. Erickson, David J. Neidhart, John H. VanDrie et al. · Science · 1990 · 528 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

ABT-378, a Highly Potent Inhibitor of the Human Immunodeficiency Virus Protease

Hing L. Sham, Dale J. Kempf, Akhteruzammen Molla et al. · Antimicrobial Agents and Chemotherapy · 1998 · 470 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16