Varghese John - Concepedia

Author

Varghese John

Buck Institute for Research on Aging ORCID

Also Known As

V A John, V John, V. A. JOHN, V. JOHN, V. John, Varghese John

127

Publications

4.7K

Citations

H-Index

100

Concepts

All Affiliations

Buck Institute for Research on Aging University of California, Los Angeles University of California, San Francisco Sunesis (United States)National Institute on Aging

About

Varghese John is an author at Buck Institute for Research on Aging specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	17	22	1.6K
2	Natural Sciences	11	12	1.9K
3	Social Sciences	5	5	2.5K
4	Engineering	3	3	55
5	Health Sciences	1	1	26

Varghese John

Publications

4.1K

Citations

H-Index

Page 1

	Year	Citations
Purification and cloning of amyloid precursor protein β-secretase from human brain Sukanto Sinha, John P. Anderson, Robin Barbour, Nature Neurodegenerative DiseasesProtein SecretionMolecular NeuroscienceBiochemistryProtein Folding	1999	1.6K
Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain Harry F. Dovey, Varghese John, J. P. Anderson, Journal of Neurochemistry Protein SecretionNeurochemical BiomarkersAmyloid Precursor ProteinSocial SciencesAlzheimer's Disease	2001	877
Design, Synthesis, and Crystal Structure of Hydroxyethyl Secondary Amine-Based Peptidomimetic Inhibitors of Human β-Secretase Michel Maillard, Roy K. Hom, Timothy E. Benson, Journal of Medicinal Chemistry	2007	110
Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer’s Disease Brain Tissue Reveals Disease-Associated Signatures Whitaker Cohn, Mikhail Melnik, Calvin Huang, Frontiers in Pharmacology	2021	106
Neuroprotective Sirtuin ratio reversed by ApoE4 Veena Theendakara, Alexander Patent, Clare A. Peters Libeu, Proceedings of the National Academy of Sciences	2013	98
Design of Substrate-Based Inhibitors of Human β-Secretase Jay S. Tung, David L. Davis, John P. Anderson, Journal of Medicinal Chemistry	2001	88
Posiphen as a candidate drug to lower CSF amyloid precursor protein, amyloid-β peptide and τ levels: target engagement, tolerability and pharmacokinetics in humans Maria L. Maccecchini, Mee Young Chang, Catherine Pan, Journal of Neurology Neurosurgery & Psychiatry	2012	85
Design and Synthesis of Hydroxyethylene-Based Peptidomimetic Inhibitors of Human β-Secretase Roy K. Hom, Andrea F. Gailunas, Shumeye Mamo, Journal of Medicinal Chemistry Medicinal ChemistryHuman β-SecretaseBioorganic ChemistryPharmaceutical ScienceBiochemistry	2003	80
Design and Synthesis of Statine-Based Cell-Permeable Peptidomimetic Inhibitors of Human β-Secretase Roy K. Hom, Larry Y. Fang, Shumeye Mamo, Journal of Medicinal Chemistry Protein SecretionHuman β-SecretaseBiochemistryG Protein-coupled ReceptorNatural Sciences	2003	78
Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair Ruzanna Shkhyan, Ben Van Handel, Jacob Bogdanov, Annals of the Rheumatic Diseases	2018	56

Page 1