Concepedia

Simeon Bowers

SB

Statistics

Publications

23

Citations

889

H-Index

18

Active since

1997

Affiliations

Sunesis (United States)(Current)

University of Washington

University of Birmingham

Simeon Bowers is an author at Sunesis (United States) specializing in pharmacology, drug discovery, and medicinal chemistry.

Publications per year

1997–2018

23

Publications

23

Antibody–Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs

Christopher R. Behrens, Edward Ha, Lawrence Chinn et al. · Molecular Pharmaceutics · 2015 · 153 citations · Full text

, , +17

Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2<i>S</i>,3<i>R</i>)-<i>N</i>-((<i>S</i>)-3-(Cyclopent-1-en-1-yl)-1-((<i>R</i>)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-((<i>S</i>)-2-(2-morpholinoacetamido)propanamido)propenamide)

Henry W. B. Johnson, Eric Lowe, Janet L. Anderl et al. · Journal of Medicinal Chemistry · 2018 · 100 citations · Full text

, , +11

Trityl ethers in oligosaccharide synthesis: A novel strategy for the convergent assembly of oligosaccharides

Geert‐Jan Boons, Simeon Bowers, Diane M. Coe · Tetrahedron Letters · 1997 · 49 citations

, , +13

Selective and Brain‐Permeable Polo‐like Kinase‐2 (Plk‐2) Inhibitors That Reduce α‐Synuclein Phosphorylation in Rat Brain

Danielle L. Aubele, Roy K. Hom, Marc Adler et al. · ChemMedChem · 2013 · 49 citations

, , +12

Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model

Anh P. Truong, G. Toth, Gary D. Probst et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 48 citations · Full text

, , +7

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