Pamela S. Keim - Concepedia

Concepedia

Author

Pamela S. Keim

University of Chicago

Also Known As

PAMELA S. KEIM, Pamela Keim, Pamela S Keim, Pamela S. Keim

23

Publications

5.1K

Citations

16

H-Index

40

Concepts

All Affiliations

University of Chicago Sunesis (United States)Athena Group (United States)

PS

About

Pamela S. Keim is an author at University of Chicago specializing in natural sciences, biochemistry, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	10	10	1.9K
2	Biochemistry	9	9	1.9K
3	Medicine	6	6	364
4	Social Sciences	2	2	1.8K
5	Public Health	1	1	43

Pamela S. Keim

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16

Publications

5.1K

Citations

15

H-Index

	Year	Citations
Purification and cloning of amyloid precursor protein β-secretase from human brain Sukanto Sinha, John P. Anderson, Robin Barbour, Nature Neurodegenerative DiseasesProtein SecretionMolecular NeuroscienceBiochemistryProtein Folding	1999	1.6K
Phosphorylation of Ser-129 Is the Dominant Pathological Modification of α-Synuclein in Familial and Sporadic Lewy Body Disease John P. Anderson, Donald E. Walker, Jason Goldstein, Journal of Biological Chemistry	2006	1.4K
Cleavage of Amyloid β Peptide During Constitutive Processing of Its Precursor Fred Esch, Pamela S. Keim, Eric C. Beattie, Science	1990	1.4K
Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells John P. Anderson, Fred Esch, Pamela S. Keim, Neuroscience Letters Molecular NeuroscienceAlzheimer's DiseaseDementiaNeuronal Pc-12 CellsNeurochemical Biomarkers	1991	213
Arylphorin, a new protein from Hyalophora cecropia: Comparisons with calliphorin and manducin William H. Telfer, Pamela S. Keim, John H. Law Insect Biochemistry BiochemistryNatural SciencesNew ProteinMicrobiologyHyalophora Cecropia	1983	150
Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease Guriqbal S. Basi, Susanna S. Hemphill, Elizabeth Brigham, Alzheimer s Research & Therapy	2010	50
Partial structural analysis of the basic chromosomal protein of rat spermatozoa W. Stephen Kistler, Pamela S. Keim, Robert L. Heinrikson Biochimica et Biophysica Acta (BBA) - Protein Structure SpermatogenesisChromatinInfertilityCell DivisionPartial Structural Analysis	1976	43
Design, synthesis, and structure–activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline γ-secretase inhibitors Anh P. Truong, Danielle L. Aubele, Gary D. Probst, Bioorganic & Medicinal Chemistry Letters Structure–activity RelationshipMedicinal ChemistryPharmaceutical ScienceBiochemistryEfficacious Pyrazole/sulfonamide	2009	36
Discovery of (<i>R</i>)-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1<i>H</i>-pyrazolo[4,3-<i>c</i>]quinoline (ELND006) and (<i>R</i>)-4-Cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2<i>H</i>-pyrazolo[4,3-<i>c</i>]quinoline (ELND007): Metabolically Stable γ-Secretase Inhibitors that Selectively Inhibit the Production of Amyloid-β over Notch Gary D. Probst, Danielle L. Aubele, Simeon Bowers, Journal of Medicinal Chemistry Molecular PharmacologyMedicinal ChemistrySynthetic StrategyAβ GenerationBiochemistry	2013	32
Crotalus adamanteus phospholipase A2-α: Subunit structure, NH2-terminal sequence, and homology with other phospholipases Francis H.C. Tsao, Pamela S. Keim, Robert L. Heinrikson Archives of Biochemistry and Biophysics BiochemistryNatural SciencesMolecular BiologyNh2-terminal SequenceOther Phospholipases	1975	28

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