Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase

Structure of the Tie2 RTK Domain

Lisa M. Shewchuk, Anne M. Hassell, Byron Ellis et al. · Structure · 2000 · 145 citations · Full text

Computational Topology, Tie2 Rtk Domain

Ablation of the spindle assembly checkpoint by a compound targeting Mps1

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Cell Division, Natural Sciences, Molecular Biology +3

Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase

Hui Yang, Teresa F. Burke, Jack Dempsey et al. · FEBS Letters · 2005 · 114 citations

Molecular Biology, Cell Death, Cytoskeleton +17

Evolution of a Highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor

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Molecular Biology, Pharmacotherapy, Chemical Biology +21

Di-2-Pyridyl thionocarbonate. A new reagent for the preparation of isothiocyanates and carbodiimides.

Sunggak Kim, Kyu Yang Yi · Tetrahedron Letters · 1985 · 80 citations

Engineering, Organic Chemistry, Di-2-pyridyl Thionocarbonate +7