Brian L. Hodous - Concepedia

Author

Brian L. Hodous

Amgen (United States)

Also Known As

B. Hodous, B.L. Hodous, Brian Hodous, Brian L. Hodous, Hodous, B.L.

Publications

Citations

H-Index

Concepts

All Affiliations

Amgen (United States)Blueprint Medicines (United States)Massachusetts Institute of Technology

About

Brian L. Hodous is an author at Amgen (United States) specializing in pharmacology, medicine, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	606
2	Natural Sciences	7	7	414
3	Biochemistry	4	4	155
4	Engineering	3	3	300
5	Allergy	1	1	67

Brian L. Hodous

Publications

Citations

H-Index

Page 1

	Year	Citations
First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway Margit Hagel, Chandra Miduturu, Michael P. Sheets, Cancer Discovery	2015	305
Enantioselective Staudinger Synthesis of β-Lactams Catalyzed by a Planar-Chiral Nucleophile Brian L. Hodous, Gregory C. Fu Journal of the American Chemical Society	2002	245
A precision therapy against cancers driven by <i>KIT/PDGFRA</i> mutations Erica N Evans, Alexandra K. Gardino, Joseph L. Kim, Science Translational Medicine	2017	209
Catalytic Asymmetric Staudinger Reactions to Form β-Lactams: An Unanticipated Dependence of Diastereoselectivity on the Choice of the Nitrogen Substituent Elaine C. Lee, Brian L. Hodous, E. Bergin, Journal of the American Chemical Society	2005	190
Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases Richard D. Caldwell, Hui Qiu, Ben Askew, Journal of Medicinal Chemistry Novel TherapyMedicineTyrosine KinaseHighly SelectiveImmunology	2019	136
Enantioselective Addition of Alcohols to Ketenes Catalyzed by a Planar-Chiral Azaferrocene: Catalytic Asymmetric Synthesis of Arylpropionic Acids Brian L. Hodous, J. Craig Ruble, Gregory C. Fu Journal of the American Chemical Society Catalytic Asymmetric SynthesisEngineeringNatural SciencesDiversity-oriented SynthesisPlanar-chiral Azaferrocene	1999	135
Enantioselective Addition of Amines to Ketenes Catalyzed by a Planar-Chiral Derivative of PPY: Possible Intervention of Chiral Brønsted-Acid Catalysis Brian L. Hodous, Gregory C. Fu Journal of the American Chemical Society Chiral Brønsted-acid CatalysisDerivativesEngineeringEnantioselective SynthesisPlanar-chiral Catalyst	2002	132
Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines Marc Payton, Tammy L. Bush, Grace Chung, Cancer Research Cell DeathNovel PotentCancer BiologyGliomaTumor Biology	2010	118
Evolution of a Highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor Brian L. Hodous, Stephanie Geuns-Meyer, Paul E. Hughes, Journal of Medicinal Chemistry Molecular BiologyPharmacotherapyChemical BiologyTumor AngiogenesisTumor Biology	2007	91
Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck: Synthesis, SAR, and in Vivo Anti-Inflammatory Activity Erin F. DiMauro, John Newcomb, Joseph J. Nunes, Journal of Medicinal Chemistry Pharmaceutical ScienceImmunologyImmunologic MechanismPharmacotherapyImmunotherapeutics	2006	67

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