Michael P. Sheets

Discovery of a Mutant-Selective Covalent Inhibitor of EGFR that Overcomes T790M-Mediated Resistance in NSCLC

Annette O. Walter, Robert Tjin Tham Sjin, Henry J. Haringsma et al. · Cancer Discovery · 2013 · 627 citations · Full text

Medicine, Oncology, Pharmacology +17

Precision Targeted Therapy with BLU-667 for <i>RET</i>-Driven Cancers

Vivek Subbiah, Justin F. Gainor, Rami Rahal et al. · Cancer Discovery · 2018 · 393 citations

Medicine, Oncology, Pharmacology +17

First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway

Margit Hagel, Chandra Miduturu, Michael P. Sheets et al. · Cancer Discovery · 2015 · 315 citations · Full text

Medicine, Oncology, Pharmacology +17

Inhibition of Btk with CC-292 Provides Early Pharmacodynamic Assessment of Activity in Mice and Humans

Erica Evans, Richland Tester, Sharon Aslanian et al. · Journal of Pharmacology and Experimental Therapeutics · 2013 · 219 citations

Medicine, Immunology, Pharmacology +17

3,5-Bis(trifluoromethyl)pyrazoles:  A Novel Class of NFAT Transcription Factor Regulator

Stevan W. Djurić, Nwe Y. BaMaung, Anwer Basha et al. · Journal of Medicinal Chemistry · 2000 · 120 citations

Life Sciences, Immunology, Pharmacology +16