Margit Hagel - Concepedia

Concepedia

Author

Margit Hagel

Beth Israel Deaconess Medical Center ORCID

Also Known As

M. Hagel, Margit Hagel, Marlene Hagel

74

Publications

1.7K

Citations

12

H-Index

40

Concepts

All Affiliations

Beth Israel Deaconess Medical Center Harvard University Infinity Pharmaceuticals (United States)Syracuse University

MH

About

Margit Hagel is an author at Beth Israel Deaconess Medical Center specializing in medicine, pharmacology, and pharmacotherapy.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	611
2	Natural Sciences	2	2	120
3	Cell Biology	2	2	98
4	Biochemistry	1	1	92
5	Cellular Physiology	1	1	65

Margit Hagel

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12

Publications

1.7K

Citations

12

H-Index

	Year	Citations
The Adaptor Protein Paxillin Is Essential for Normal Development in the Mouse and Is a Critical Transducer of Fibronectin Signaling Margit Hagel, Elizabeth George, Ann Kim, Molecular and Cellular Biology	2002	326
First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway Margit Hagel, Chandra Miduturu, Michael P. Sheets, Cancer Discovery	2015	305
Discovery of a Potent and Orally Active Hedgehog Pathway Antagonist (IPI-926) Martin Tremblay, André Lescarbeau, Michael J. Grogan, Journal of Medicinal Chemistry Medicinal ChemistryCompound 28Pharmaceutical ScienceChemoprevention StrategyMedicine	2009	250
First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma Richard D. Kim, Debashis Sarker, Tim Meyer, Cancer Discovery	2019	239
Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin Sheila Μ. Thomas, Margit Hagel, Christopher E. Turner Journal of Cell Science	1999	156
Semisynthetic Cyclopamine Analogues as Potent and Orally Bioavailable Hedgehog Pathway Antagonists Martin Tremblay, Marta Nevalainen, Somarajan Nair, Journal of Medicinal Chemistry Hedgehog AntagonistsMedicinal ChemistryPharmacological StudyMedicineNew Cyclopamine Analogues	2008	106
Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine Margit Hagel, Deqiang Niu, Thia St Martin, Nature Chemical Biology Selective Irreversible InhibitionBiochemistryProtein FoldingNatural SciencesMedicine	2010	92
Regulation of Rho and Rac Signaling to the Actin Cytoskeleton by Paxillin during <i>Drosophila</i> Development Guang‐Chao Chen, Brian Turano, Paul J. Ruest, Molecular and Cellular Biology Cdi BelongsLim KinaseDevelopmental BiologySignal TransductionSignaling Pathway	2005	65
Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K–specific inhibition Eric T. Baldwin, Matthias Götte, Egor P. Tchesnokov, Proceedings of the National Academy of Sciences Crystal StructureViral ReplicationViral Polymerase MechanismImmunologyMolecular Biology	2022	37
Protection against Anoikis and Down-regulation of Cadherin Expression by a Regulatable β-Catenin Protein Zhigang Weng, Mei Xin, Lourdes Pablo, Journal of Biological Chemistry	2002	35

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