André Lescarbeau - Concepedia

Author

André Lescarbeau

Infinity Pharmaceuticals (United States)ORCID

Also Known As

Andre Lescarbeau, André Lescarbeau, Lescarbeau, Andre

Publications

677

Citations

H-Index

Concepts

All Affiliations

Infinity Pharmaceuticals (United States)Relay Therapeutics (United States)D. E. Shaw Research Columbia University

About

André Lescarbeau is an author at Infinity Pharmaceuticals (United States) specializing in drug discovery, pharmacotherapy, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	476
2	Natural Sciences	2	2	92
3	Biochemistry	2	2	92
4	Engineering	1	1	12
5	Cell Biology	1	1	80

André Lescarbeau

Publications

658

Citations

H-Index

Page 1

	Year	Citations
Discovery of a Potent and Orally Active Hedgehog Pathway Antagonist (IPI-926) Martin Tremblay, André Lescarbeau, Michael J. Grogan, Journal of Medicinal Chemistry Medicinal ChemistryCompound 28Pharmaceutical ScienceChemoprevention StrategyMedicine	2009	250
Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate Catherine A. Evans, Tao Liu, André Lescarbeau, ACS Medicinal Chemistry Letters ImmunologyRobust Inhibition-γ InhibitorPharmacotherapyImmuno-oncology Clinical Candidate	2016	146
Synthetic Silvestrol Analogues as Potent and Selective Protein Synthesis Inhibitors Tao Liu, Somarajan Nair, André Lescarbeau, Journal of Medicinal Chemistry Drug TargetSimplified AnaloguesCompounds 74Molecular BiologyProtein Translation	2012	80
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia Andreas Varkaris, Ermira Pazolli, Hakan Günaydin, Cancer Discovery	2023	80
Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2 Heike Schönherr, Pelin Ayaz, Alexander M. Taylor, Proceedings of the National Academy of Sciences	2024	53
Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors Alexander M. Taylor, Bret R. Williams, Fabrizio Giordanetto, Journal of Medicinal Chemistry	2023	37
A Design of Experiments Approach to a Robust Final Deprotection and Reactive Crystallization of IPI-926, A Novel Hedgehog Pathway Inhibitor Theodore A. Martinot, Brian C. Austad, Alexandre Côté, Organic Process Research & Development Experiments ApproachReactive CrystallizationEngineeringMolecular BiologyChemistry	2015	12

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