Concepedia

Author

Ermira Pazolli

Washington University in St. LouisORCID

Also Known As

E Pazolli, E. Pazolli, Ermira Pazolli, Pazolli, Ermira

135

Publications

1.5K

Citations

12

H-Index

14

Concepts

All Affiliations

Washington University in St. LouisMoffitt Cancer CenterMemorial Sloan Kettering Cancer CenterRelay Therapeutics (United States)Broad Institute
EP

About

Ermira Pazolli is an author at Washington University in St. Louis specializing in tumor biology, cancer research, and cancer biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

2

2

638

2

Cell Biology

2

2

638

3

Cancer Cell Biology

1

1

147

4

Cancer Genetics

1

1

491

5

Developmental Biology

1

1

147

Ermira Pazolli

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11

Publications

1.5K

Citations

11

H-Index

YearCitations

H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

Michael Seiler, Akihide Yoshimi, Rachel Darman,

Nature Medicine

2018

491

Chromatin Remodeling Underlies the Senescence-Associated Secretory Phenotype of Tumor Stromal Fibroblasts That Supports Cancer Progression

Ermira Pazolli, Elise Alspach, Agnieszka Milczarek,

Cancer Research

2012

188

AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and <i>ESR1</i> -Mutant Breast Tumors in Preclinical Models

Hazel M. Weir, Robert H. Bradbury, Mandy Lawson,

Cancer Research

2016

174

p38MAPK Plays a Crucial Role in Stromal-Mediated Tumorigenesis

Elise Alspach, Kevin C. Flanagan, Xianmin Luo,

Cancer Discovery

2014

167

Senescent Stromal-Derived Osteopontin Promotes Preneoplastic Cell Growth

Ermira Pazolli, Xianmin Luo, Sarah Brehm,

Cancer Research

2009

147

Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia

Andreas Varkaris, Ermira Pazolli, Hakan Günaydin,

Cancer Discovery

2023

80

Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators

Daniel Aird, Teng Teng, Chia‐Ling Huang,

Nature Communications

2019

71

Osteopontin Stimulates Preneoplastic Cellular Proliferation Through Activation of the MAPK Pathway

Xianmin Luo, Megan K. Ruhland, Ermira Pazolli,

Molecular Cancer Research

2011

57

Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary <i>PIK3CA</i> Mutations

Andreas Varkaris, Ferran Fece de la Cruz, Elizabeth E. Martin,

Cancer Discovery

2023

49

H3B-8800, an Orally Bioavailable Modulator of the SF3b Complex, Shows Efficacy in Spliceosome-Mutant Myeloid Malignancies

Silvia Buonamici, Akihide Yoshimi, Michael W. Thomas,

Blood

2016

33

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