Heike Schönherr

RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across <i>FGFR2</i> Alterations and Resistance Mutations

Vivek Subbiah, Vaibhav Sahai, Dejan Maglic et al. · Cancer Discovery · 2023 · 119 citations · Full text

Medicine, Oncology, Pharmacology +16

Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2

Heike Schönherr, Pelin Ayaz, Alexander M. Taylor et al. · Proceedings of the National Academy of Sciences · 2024 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Direct and Highly Enantioselective Iso-Pictet–Spengler Reactions with α-Ketoamides: Access to Underexplored Indole Core Structures

Heike Schönherr, James L. Leighton · Organic Letters · 2012 · 63 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Synthesis of Antioxidants for Prevention of Age-Related Macular Degeneration

Dharati Joshi, James B. Field, John D. Murphy et al. · Journal of Natural Products · 2013 · 36 citations · Full text

Medicine, Ophthalmology, Pharmacology +15

A Chemoenzymatic Approach to the Stereocontrolled Synthesis of the C1–C11 fragment of (+)‐Peloruside A

Heike Schönherr, Jan Mollitor, Christoph Schneider · European Journal of Organic Chemistry · 2010 · 13 citations

Pharmacy, Biochemistry, Chemistry +15