Concepedia

Alexandra K. Gardino

AK

13

Publications

1.5K

Citations

13

H-Index

2003

Active since

Affiliations

Blueprint Medicines (United States)(Current)

Brandeis University

Massachusetts Institute of Technology

Harvard University

Howard Hughes Medical Institute

Alexandra K. Gardino is an author at Blueprint Medicines (United States) specializing in medicine, molecular biology, and cell biology.

Top concepts

Publications per year

2003–2019

13

Publications

13

Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks

Michael J. Lee, Albert S. Ye, Alexandra K. Gardino et al. · Cell · 2012 · 676 citations · Full text

, , +9

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint

Marcel A.T.M. van Vugt, Alexandra K. Gardino, Rune Linding et al. · PLoS Biology · 2010 · 227 citations · Full text

, , +15

A precision therapy against cancers driven by <i>KIT/PDGFRA</i> mutations

Erica N Evans, Alexandra K. Gardino, Joseph L. Kim et al. · Science Translational Medicine · 2017 · 209 citations

Transient Non-native Hydrogen Bonds Promote Activation of a Signaling Protein

Alexandra K. Gardino, Janice Villali, Aleksandr Kivenson et al. · Cell · 2009 · 106 citations · Full text

, , +8

Robust Activity of Avapritinib, Potent and Highly Selective Inhibitor of Mutated KIT, in Patient-derived Xenograft Models of Gastrointestinal Stromal Tumors

Yemarshet K. Gebreyohannes, Agnieszka Woźniak, Madalina-Elena Zhai et al. · Clinical Cancer Research · 2018 · 75 citations · Full text

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