Alexandra K. Gardino

Author

Blueprint Medicines (United States)

Also Known As

A. Gardino, A.K. Gardino, Alexandra Gardino, Alexandra K Gardino, Alexandra K. Gardino, Alexandra K. Gardino

Publications

2.1K

Citations

H-Index

Concepts

All Affiliations

Blueprint Medicines (United States)Brandeis University Massachusetts Institute of Technology Harvard University Howard Hughes Medical Institute

About

Alexandra K. Gardino is an author at Blueprint Medicines (United States) specializing in medicine, molecular biology, and cell biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	8	8	1.2K
2	Natural Sciences	4	4	401
3	Cell Biology	4	4	952
4	Biochemistry	2	2	143
5	Biomolecular Engineering	1	1	21

Alexandra K. Gardino

Publications

1.5K

Citations

H-Index

Page 1

	Year	Citations
Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks Michael J. Lee, Albert S. Ye, Alexandra K. Gardino, Cell OncologyChemoprevention StrategyMedicineApoptosisCell Death	2012	676
A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint Marcel A.T.M. van Vugt, Alexandra K. Gardino, Rune Linding, PLoS Biology ChromatinGenome InstabilityCell RegulationCell DivisionMedicine	2010	227
A precision therapy against cancers driven by <i>KIT/PDGFRA</i> mutations Erica N Evans, Alexandra K. Gardino, Joseph L. Kim, Science Translational Medicine	2017	209
Transient Non-native Hydrogen Bonds Promote Activation of a Signaling Protein Alexandra K. Gardino, Janice Villali, Aleksandr Kivenson, Cell Signal TransductionMolecular PhysiologyBiochemistrySignaling PathwaySignaling Protein	2009	106
Robust Activity of Avapritinib, Potent and Highly Selective Inhibitor of Mutated KIT, in Patient-derived Xenograft Models of Gastrointestinal Stromal Tumors Yemarshet K. Gebreyohannes, Agnieszka Woźniak, Madalina-Elena Zhai, Clinical Cancer Research	2018	75
Functional Dynamics of Response Regulators Using NMR Relaxation Techniques Alexandra K. Gardino, Dorothee Kern Methods in enzymology on CD-ROM/Methods in enzymology Relaxation ProcessMagnetic ResonanceMolecular BiologyFunctional DynamicsProtein Nmr	2007	44
Inhibitory effects of midostaurin and avapritinib on myeloid progenitors derived from patients with KIT D816V positive advanced systemic mastocytosis Johannes Lübke, Nicole Naumann, Sebastian Kluger, Leukemia	2019	44
The NMR Solution Structure of BeF3−-Activated Spo0F Reveals the Conformational Switch in a Phosphorelay System Alexandra K. Gardino, Brian F. Volkman, Ho S. Cho, Journal of Molecular Biology Nmr Solution StructureBiochemistryMedicineNatural SciencesMagnetic Resonance	2003	37
Segmented Transition Pathway of the Signaling Protein Nitrogen Regulatory Protein C Ming Lei, Janice Velos, Alexandra K. Gardino, Journal of Molecular Biology Protein FunctionSignal TransductionMolecular PathwayReactive Nitrogen SpecieNatural Sciences	2009	31
Abstract 791: BLU-285, the first selective inhibitor of PDGFRα D842V and KIT Exon 17 mutants Erica N Evans, Brian L. Hodous, Alexandra K. Gardino, Cancer Research Molecular BiologyPathologyGastric GistPdgfrα D842vTumor Biology	2015	21

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